Pharmacokinetic/Pharmacodynamic dataset containing 200 subjects with single bolus dose

Pharmacokinetic/Pharmacodynamic dataset containing 200 subjects with single bolus dose.

Usage

pkpdData

Format

A data frame with 2600 rows and 5 variables:

ID

Subject ID

Time

Nominal Time

Dose

Amount of dose

CObs

Observations of drug concentration in blood

EObs

Observations of drug effect

Source

The data is simulated using a PKPD model with PK described by a one-compartment model with IV bolus and PD described by an indirect response model with the loss inhibited.