PK model mapping parameters

PK model mapping parameters

Usage

pkmodel_MappingParameters(
  ID = NULL,
  Time = NULL,
  A1 = NULL,
  Aa = NULL,
  A = NULL,
  A1_Rate = NULL,
  A1_Duration = NULL,
  Aa_Rate = NULL,
  Aa_Duration = NULL,
  A_Rate = NULL,
  A_Duration = NULL,
  A1Strip = NULL,
  CObs = NULL,
  C1Obs = NULL,
  A0Obs = NULL
)

Arguments

ID

Column mapping argument for input dataset column(s) that identify individual data profiles. Only applicable to population models isPopulation = TRUE.

Time

Column mapping argument that represents the input dataset column for the relative time used in a study and only applicable to time-based models.

A1

Column mapping argument that represents the input dataset column for the amount of drug administered. Only applicable to the following types of models:

• Models with absorption = "Intravenous" and parameterization set to either "Clearance","Micro", or "Macro"

• Models with absorption set to either "Gamma", "InverseGaussian", or "Weibull"

Aa

Column mapping argument that represents the input dataset column for the amount of drug administered and only applicable to models with absorption = "FirstOrder".

A

Column mapping argument that represents the input dataset column for the amount of drug administered and only applicable to models with absorption = "Intravenous" and parameterization = "Macro1".

A1_Rate

Column mapping argument that represents the input dataset column for the rate of drug administered. Only applicable to the following types of models:

• Models with absorption = "Intravenous", infusionAllowed = TRUE and parameterization set to either "Clearance","Micro" or "Macro"

• Models with absorption set to either "Gamma", "InverseGaussian", or "Weibull" and infusionAllowed = TRUE

A1_Duration

Column mapping argument that represents the input dataset column for the duration of drug administered. Only applicable to the following types of models:

• Models with absorption = "Intravenous", infusionAllowed = TRUE with isDuration = TRUE and parameterization set to either "Clearance","Micro" or "Macro"

• Models with absorption set to either "Gamma", "InverseGaussian", or "Weibull" and infusionAllowed = TRUE with isDuration = TRUE

Aa_Rate

Column mapping argument that represents the input dataset column for the rate of drug administered and only applicable to models with absorption = "FirstOrder", infusionAllowed = TRUE.

Aa_Duration

Column mapping argument that represents the input dataset column for the duration of drug administered and only applicable to models with absorption = "FirstOrder", infusionAllowed = TRUE, and isDuration = TRUE.

A_Rate

Column mapping argument that represents the input dataset column for the rate of drug administered and only applicable to models with absorption = "Intravenous", infusionAllowed = TRUE, and parameterization = "Macro1".

A_Duration

Column mapping argument that represents the input dataset column for the duration of drug administered and only applicable to models with absorption = "Intravenous", infusionAllowed = TRUE, isDuration = TRUE, and parameterization = "Macro1".

A1Strip

Column mapping argument that represents the input dataset column for the stripping dose and only applicable to models with parameterization = "Macro".

CObs

Column mapping argument that represents the input dataset column for the observations of drug concentration in the central compartment and only applicable to models with parameterization being either set to either "Clearance" or "Micro".

C1Obs

Column mapping argument that represents the input dataset column for the observations of drug concentration in the central compartment and only applicable to models with parameterization being either set to either "Macro" or "Macro1".

A0Obs

Column mapping argument that represents the input dataset column for the observed amount of drug in the elimination compartment. (hasEliminationComp = TRUE).

Column mapping

Note that quoted and unquoted column names are supported. Please see colMapping.