Lesson 9: RsNLME Case Study
In Lesson 9 we provide a case study of RsNLME,
demonstrating an end to end workflow using the suite of R packages and
Shiny applications developed by Certara.
Webinar Overview
The bioequivalence of biosimilars is difficult to prove using traditional NCA approaches due to non-linear PK, or/and long half-life as such a lot of research has been ongoing to conduct a model-based approach.
The model-based approach operation characteristics was studied using a simulation-reestimation approach.
In this webinar we will cover:
- How to design a simulation re-estimation study
- How to write efficient R and RsNLME workflows that build the dataset, fit the model, conduct the required analysis and collect and compile results
- How to present the results using graphics and tables